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Filtered Search Results
Medchemexpress LLC HY-19792 10mg , Mertansine CAS:139504-50-0 Purity:>98%
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HY-19792 10mg Mertansine CAS: 139504-50-0 Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. Mertansine can be attached to a monoclonal antibody with a linker to create an antibody-drug conjugate (ADC). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Fosbretabulin disodium | 168555-66-6 | 99.6% | 440.29 | 100MG
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Fosbretabulin disodium is a tubulin destabilizing agent and a Combretastatin A4 proagent. It selectively targets endothelial cells to induce regression of nascent tumor neovessels, reduce tumor blood flow, and cause central tumor necrosis. This compound shows significant biological activity in vitro against various cancer cell lines and in vivo by increasing mean arterial blood pressure and reducing tumor blood flow.
- Inhibits growth of multiple cancer cell lines (leukemia, pancreas, neuroblast, thyroid, lung-NSC, prostate, pharynx)
- Increases mean arterial blood pressure
- Reduces blood flow in tumors
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Medchemexpress LLC HY-18708 10mg Medchemexpress, Erdafitinib CAS:1346242-81-6 Purity:>98%
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Medchemexpress, HY-18708 10mg Erdafitinib CAS:1346242-81-6 Erdafitinib (JNJ-42756493) is a potent and orally available FGFR family inhibitor; inhibits FGFR1/2/3/4 with IC50s of 1.2, 2.5, 3.0 and 5.7 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC N-methylmethanesulfonamide chromanol derivative | 223749-46-0 | MFCD12756323 | 100.0% | 411.44 g·mol⁻¹ | C17H24F3NO5S | 50 MG
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HMR 1556 is a chromanol-derived research compound that potently and selectively blocks the slowly activating delayed rectifier potassium current (IKs). It is used as a pharmacological tool in cardiac electrophysiology and pharmacology to probe IKs-mediated repolarization in vitro and in vivo. Reported IC50 values include 10.5 nM (canine left ventricular myocytes) and 34 nM (guinea pig left ventricular myocytes).
- Potent IKs blockade at low-nanomolar concentrations.
- Selective for IKs with limited off-target activity at pharmacologically relevant doses.
- Suitable for in vitro and in vivo electrophysiology and pharmacology studies.
- High-purity solid form, soluble in DMSO for stock solutions.
- Documented solubility and storage conditions for reliable experimental use.
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eMolecules 872511-34-7 | Medchem Express | Infigratinib | 5mg | 446262728 | HY-13311 | MFCD22123241 | 560.48 | C26H31Cl2N7O3
Medchem Express | Infigratinib | 5mg | 446262728 | HY-13311 | 872511-34-7 | MFCD22123241 | 560.480 | C26H31Cl2N7O3
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Medchemexpress LLC 6-(4-chlorophenyl)-2,3-dihydro-N-[(1S)-2-hydroxy-1-methylethyl]-2-(1-methyl-1H-pyrazol-4-yl)-3-oxo-4 | 2242464-44-2 | MFCD32693912 | >98.0% | C18H18ClN5O3 | 10MG
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BAY 2416964 is a small-molecule aryl hydrocarbon receptor (AhR) antagonist developed as a clinical-stage oncology candidate. It inhibits AhR signaling in vitro, has shown cellular potency in reported assays, and has been evaluated in early-phase clinical studies as an immunomodulatory agent to enhance anti-tumor immune responses.
- Small-molecule aryl hydrocarbon receptor antagonist.
- Demonstrated cellular potency, reported IC50 ~341 nM.
- Investigated in early-phase clinical studies for solid tumors.
- High chemical purity typical for supplied samples (>98.0%).
- Suitable for preclinical pharmacology and mechanism-of-action studies.
- Molecular formula C18H18ClN5O3; molecular weight ~387.8.
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eMolecules 1234015-52-1 | Medchem Express | Prexasertib | 5mg | 446268931 | HY-18174 | MFCD25977016 | 365.397 | C18H19N7O2
Ambeed | (3R4S)-4-(4-Fluorobenzamido)-6-(4-(oxetan-3-yl)piperazin-1-yl)chroman-3-yl methylcarbamate | 1mg | 525216039 | A473978 | 1373215-15-6 | MFCD28502827 | 484.528 | C25H29FN4O5
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Medchemexpress LLC Tucatinib hemiethanolate | 1429755-56-5 | 98.8% | 503.57 | 100 MG
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Tucatinib hemiethanolate is a potent, orally active, and selective HER2 inhibitor. With an IC50 of 8 nM, it selectively targets HER2, showing approximately 500-fold selectivity over EGFR in cell-based assays. This compound is intended for research use only.
- Potent, orally active, and selective HER2 inhibitor
- Selectively inhibits receptor tyrosine kinase HER2 relative to EGFR
- Blocks proliferation and phosphorylation of HER2 and its downstream effector Akt
- Demonstrated anti-tumor activity and improved survival in animal models
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Medchemexpress LLC HY-129554 5mg Medchemexpress, cis-9,10-Epoxystearic acid CAS:24560-98-3 Purity:>98%
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Medchemexpress, HY-129554 5mg cis-9,10-Epoxystearic acid CAS:24560-98-3 cis-9,10-Epoxystearic acid (cis-9,10-Epoxyoctadecanoic acid) is an endogenous constituent in human blood and urine. cis-9,10-Epoxystearic acid (cis-9,10-Epoxyoctadecanoic acid) can be produced from oleic acid by enzymic and non-enzymic epoxidation. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-16966 100mg , SBI-0206965 CAS:1884220-36-3 Purity:98%
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Medchemexpress, HY-16966 100mg SBI-0206965 CAS:1884220-36-3 Formula:C21H21BrN4O5 Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-16582A 100mg , LDE225 NVP-LDE 225;Erismodegib CAS:956697-53-3 Purity:98%
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Medchemexpress, HY-16582A 100mg LDE225 NVP-LDE 225;Erismodegib CAS:956697-53-3 Formula:C26H26F3N3O3 IC50: 1.3 nM (mSmo), 2.5 nM (hSmo) Purity:98% LDE225 is a potent and selective Smo antagonist with IC 50 of 1.3 nM and 2.5 nM for mouse and human Smo in binding assay, respectively. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Sigma Aldrich Fine Chemicals Biosciences Talampanel >=97% (HPLC) | 161832-65-1 | MFCD00871406 | 25MG
Talampanel >=97% (HPLC) | Purity: >=97% (HPLC) | Mol Wt: 337.37 | 161832-65-1 | MFCD00871406 | 25MG
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Medchemexpress LLC MAL-VC-PAB-DM1 10MG
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5000203098 MAL-VC-PAB-DM1 10MG
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Medchemexpress LLC Dapoxetine-d7 hydrochloride | 2699607-47-9 | 100.0% | 1 MG
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Dapoxetine-d7 hydrochloride is the deuterium labeled form of Dapoxetine hydrochloride, a short-acting selective serotonin reuptake inhibitor (SSRI). This compound is intended for research use only.
- Utilized as a tracer
- Serves as an internal standard for quantitative analysis through techniques such as NMR, GC-MS, or LC-MS
- Short-acting selective serotonin reuptake inhibitor (SSRI)
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Medchemexpress LLC HY-14895A 5mg Medchemexpress, Fabomotizole (hydrochloride) CAS:173352-39-1 Purity:>98%
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Medchemexpress, HY-14895A 5mg Fabomotizole (hydrochloride) CAS:173352-39-1 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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